An international team of scientists led by HHMI/Moore Foundation Plant Investigator Joe Ecker has sequenced the whole genomes and epigenomes of 1,001 Arabidopsis thaliana plants, sampled from geographically diverse locations.
The collection of 1,001 genomes and 1,001 epigenomes not only illuminates new aspects of the plant's evolutionary history, but also provides a comprehensive, species-wide picture of the interaction between genetic and epigenetic variation in this important model plant. Many questions about plant evolution and adaptation can be addressed with the new data.
“It’s an enormous hypothesis generator in terms of trying to understand what happens in the natural world,” explained Ecker, who directed the 1,001 epigenomes project. “In the past, we’ve made mutations in almost all genes in the laboratory. But here you’re looking at both subtle and not so subtle variants, both genetic and epigenetic, that are captured from the wild.”
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